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Crohns disease

The following articles have the tag Crohns disease

Shared genetic risk found for Crohn’s and coeliac disease

RESEARCHERS have found four common genetic risk loci after a combined meta-analysis of genome-wide data for both Crohn’s disease and coeliac disease. Both of these diseases are complex genetic traits with multiple genetic and non-genetic risk factors. Scientists from the Netherlands, the US and Canada found two shared-risk loci that had previously been independently identified for each disease – the PTPN2 and IL18RAP – and a further two, TAGAP and PUS10i. At least one in 100 people in the Western world develops coeliac disease, Crohn’s disease being far less common. Previous studies have shown coeliac ...

Australian Crohn’s disease rates revealed

AUSTRALIA has one of the world’s highest rates of Crohn’s disease, research has revealed. With the disease being almost as common as type 1 diabetes in the 20-24 years age group, doctors needed a lower threshold for aggressive investigation of GI symptoms, said Dr Jarrad Wilson, IBD Fellow at St Vincent’s Hospital, Melbourne. He told the recent Australian Gastroenterology Week conference that the first Australian population-based study of inflammatory bowel disease (IBD) incidence found a Crohn’s disease rate at 17.4/100,000, compared to 8/100,000 in Denmark. Overall IBD incidence in Australia was 29.3 per 100,000, among the highest reported internationally, but still comparable ...